The observed increased incidence of adenomas and colorectal carcinomas in men compared with women has been linked to male sex hormones, according to a new study. The authors sought to address whether the lower incidence and delayed onset in women is owing to protection by female hormones or lack of tumour-promotion by male hormones.
Patman G. Colorectal cancer: male hormones increase the incidence of colonic adenomas. Nature reviews Gastroenterology & hepatology. 2015;12(1):4. Epub 2014/11/19. doi: 10.1038/nrgastro.2014.196. PubMed PMID: 25404279.